Rickettsia typhi (mooseri) IgM Test

This test is for anyone who has been exposed to fleas or rodents and is experiencing symptoms such as persistent fever, headache, rash, or muscle aches. It looks for IgM antibodies against Rickettsia typhi (also known as Rickettsia mooseri), the bacterium that causes murine typhus. IgM antibodies are the first type of antibody the body produces after a new infection, so their presence can help indicate a recent or active infection.

Murine typhus is a flea-borne infection found worldwide, including in parts of the UK and Europe. It often causes a flu-like illness that can be mistaken for other conditions. Testing for IgM antibodies against Rickettsia typhi helps clinicians confirm or rule out this infection, particularly when there is a history of travel to endemic areas or contact with rodents or fleas.

Biomarkers included
- Rickettsia typhi (mooseri) IgM antibody: Detects the presence of IgM class antibodies produced by the immune system in response to a recent infection with Rickettsia typhi.

Why it matters
Murine typhus is treatable with appropriate antibiotics, but it can be serious if left undiagnosed. Early identification of the infection allows for timely treatment and helps distinguish it from other febrile illnesses with similar symptoms. This test provides valuable information to support clinical decision-making and appropriate patient care.

• Rickettsia typhi (mooseri) IgM antibody

No special preparation required.

For blood tests, we recommend drinking plenty of water beforehand to ensure smooth sample collection. If you are taking any regular medication, continue to do so unless advised otherwise by your doctor.