Haptoglobin Test
Detect hidden red cell destruction and preserve your iron.
The Haptoglobin Test measures the level of haptoglobin in your blood, a protein produced by the liver that binds free haemoglobin released from red blood cells. When red blood cells break down (haemolysis), haptoglobin binds the released haemoglobin to prevent it from causing kidney damage and losing iron. This test is used to investigate suspected haemolytic anaemia, monitor conditions that cause red cell destruction, and assess liver function. It is also helpful in distinguishing haemolysis from other causes of anaemia and in evaluating transfusion reactions.
Biomarkers
Haptoglobin
- Haptoglobin (Hp)
Why it matters
A low haptoglobin level can indicate increased red blood cell destruction (haemolysis), which may be due to autoimmune conditions, infections, medications, or inherited disorders such as sickle cell disease or thalassaemia. It can also be low in liver disease because the liver makes haptoglobin. A high level may be seen in inflammation, infection, or tissue damage. Measuring haptoglobin helps your doctor determine whether anaemia is caused by increased destruction or decreased production of red blood cells, guiding further tests and treatment. Early detection of haemolysis can prevent complications like gallstones, kidney damage, and iron overload.
Haptoglobin
- Haptoglobin (Hp)
No special preparation required.
For blood tests, we recommend drinking plenty of water beforehand to ensure smooth sample collection. If you are taking any regular medication, continue to do so unless advised otherwise by your doctor.
Important Clinical Information:
This test is a screening tool to monitor and support your overall health. It does not replace your GP or Consultant.
Always discuss your test results, especially any abnormal results, with your GP, who can interpret them in the context of your medical history and overall health.
Service Booking
Includes £20 phlebotomy fee
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