Anti-Ro (SS-A) Antibody Test
Clarify your autoimmune risk and protect your baby's heart.
The Anti-Ro (SS-A) antibody test is a blood test used to detect antibodies directed against the Ro (SS-A) antigen, a protein found in the nucleus of cells. These antibodies are most commonly associated with autoimmune conditions such as Sjögren's syndrome and systemic lupus erythematosus (SLE), but they can also appear in other connective tissue diseases. The test is particularly important for women who are pregnant or planning a pregnancy, as anti-Ro antibodies can cross the placenta and increase the risk of neonatal lupus and congenital heart block in the baby. It is also used to help diagnose unexplained dry eyes, dry mouth, joint pain, skin rashes, or fatigue, and to monitor disease activity in people with known autoimmune disorders.
What it screens for
- Anti-Ro (SS-A) antibodies: These are autoantibodies that target the Ro protein. Their presence can indicate an underlying autoimmune process, most notably Sjögren's syndrome (where they are found in up to 70% of cases) and SLE (in 30-40% of cases). The test helps confirm a diagnosis when symptoms are suggestive, and it guides monitoring and management, especially in pregnancy.
Why it matters
Detecting anti-Ro antibodies provides critical information for diagnosing autoimmune conditions, assessing symptom causes, and, most importantly, identifying pregnancies at risk of complications. Early awareness allows healthcare teams to arrange appropriate monitoring and care to protect both mother and baby.
- Anti-Ro (SS-A) antibody
No special preparation required.
For blood tests, we recommend drinking plenty of water beforehand to ensure smooth sample collection. If you are taking any regular medication, continue to do so unless advised otherwise by your doctor.
Important Clinical Information:
This test is a screening tool to monitor and support your overall health. It does not replace your GP or consultant.
Always discuss your test results, especially any abnormal results, with your GP, who can interpret them in the context of your medical history and overall health.