HE4 Blood Test (Ovarian Cancer Marker)
A complementary ovarian cancer marker for clearer risk assessment.
What’s tested
Pick a time
The HE4 Blood Test measures human epididymis protein 4 (HE4), a glycoprotein biomarker that can be elevated in ovarian cancer, particularly the endometrioid and serous subtypes. It is used alongside other clinical information and, where appropriate, the CA125 marker to support the assessment of ovarian cancer risk, especially in premenopausal women where CA125 alone can be less specific. The test is performed on a simple blood sample using an immunoassay method in the laboratory.
Biomarker
- Human epididymis protein 4 (HE4)
Why it matters
HE4 can add valuable information when evaluating a pelvic mass or investigating suspected ovarian cancer. Because HE4 is less likely than CA125 to rise in benign gynaecological conditions such as endometriosis or fibroids, it can help improve specificity when used as part of a combined risk assessment. Results should always be interpreted by a doctor alongside imaging, symptoms, and other test findings, and HE4 is not a standalone screening test for ovarian cancer in the general population.
No special fasting required. Drink plenty of water prior to your appointment for a smooth blood draw.
- Identification: Photo ID (Passport or Driving Licence) is only required if you need your report for official, employment, visa/travel, premarital, or Identity-Verified Certificate (IVS) purposes (not required for personal health & wellness testing).
This test provides an official, quality-assured laboratory report with reference ranges. These results are for clinical information and do not replace your GP or consultant. Always discuss abnormal results with your GP or specialist in the context of your medical history.
Related tests in Tumour Markers
View all →WhatsApp →
