GAD Ab
Pinpoint the autoimmune cause of diabetes and neurological symptoms.
Glutamic acid decarboxylase (GAD) antibodies are autoantibodies directed against the enzyme responsible for producing GABA, a key inhibitory neurotransmitter. This test measures the level of GAD antibodies in a simple blood sample using a validated immunoassay, helping to distinguish autoimmune-driven conditions from other causes.
It is most commonly requested when there is clinical suspicion of type 1 diabetes, latent autoimmune diabetes in adults (LADA), or an autoimmune neurological disorder such as stiff person syndrome, cerebellar ataxia, or limbic encephalitis. It is also used to monitor disease activity in known autoimmune diabetes and to support diagnostic workup in patients presenting with unexplained neurological or metabolic symptoms.
Biomarkers included
Autoimmune Neurology and Endocrinology
- Glutamic acid decarboxylase antibody (GAD Ab)
Why it matters
GAD antibody testing provides critical insight into whether an autoimmune process is driving a patient's diabetes or neurological symptoms. Early identification can guide appropriate treatment, prevent misdiagnosis, and help predict disease progression, enabling more targeted and timely clinical management.
Autoimmune Neurology and Endocrinology
- Glutamic acid decarboxylase antibody (GAD Ab)
No special preparation required.
For blood tests, we recommend drinking plenty of water beforehand to ensure smooth sample collection. If you are taking any regular medication, continue to do so unless advised otherwise by your doctor.
Important Clinical Information:
This test is a screening tool to monitor and support your overall health. It does not replace your GP or Consultant.
Always discuss your test results, especially any abnormal results, with your GP, who can interpret them in the context of your medical history and overall health.
Service Booking
Includes £15 phlebotomy fee
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