E2 (Oestradiol)

Oestradiol (E2) is the most potent and clinically significant form of oestrogen, playing a central role in female reproductive health, menstrual cycle regulation, and fertility. This simple blood test measures the concentration of oestradiol in your bloodstream, providing a direct window into ovarian function and hormonal balance.

This test is suitable for anyone investigating fertility concerns, monitoring ovulation induction or assisted reproduction cycles, assessing ovarian reserve, or evaluating symptoms of hormonal imbalance such as irregular periods, amenorrhoea, or menopausal transition. It is also used in men to investigate gynaecomastia or suspected oestrogen excess.

Biomarkers Included

Reproductive Hormones
- Oestradiol (E2)

Why it matters
Oestradiol is a key driver of follicular development, endometrial thickening, and the ovulatory surge that triggers egg release. Abnormal levels can indicate diminished ovarian reserve, polycystic ovary syndrome (PCOS), anovulation, or perimenopause. For those undergoing fertility treatment, accurate E2 monitoring helps clinicians adjust medication doses, time procedures precisely, and reduce the risk of ovarian hyperstimulation syndrome (OHSS). Understanding your oestradiol level empowers you and your clinician to make informed, timely decisions about your reproductive care.