Alpha-1 Antitrypsin (AAT) Blood Test
Protect your lungs and liver: know your AAT level.
The Alpha-1 Antitrypsin (AAT) Blood Test measures the level of alpha-1 antitrypsin, a protein produced mainly in the liver that protects the lungs from damage caused by enzymes released during inflammation. This test is for anyone with unexplained chronic obstructive pulmonary disease (COPD), early-onset emphysema, asthma that does not respond fully to treatment, or liver problems of unknown cause. It is also used to screen family members of someone with alpha-1 antitrypsin deficiency and to monitor people already diagnosed with the condition.
What is measured
- Alpha-1 Antitrypsin (AAT): the quantity of this protective protein in the blood. A low level can indicate alpha-1 antitrypsin deficiency, an inherited condition that raises the risk of lung and liver disease.
Why it matters
Knowing your AAT level helps identify a treatable genetic risk factor for serious lung and liver disease. Early detection allows you and your doctor to take steps to protect your lung health, avoid smoking and other irritants, and consider appropriate monitoring or treatment. It also informs family screening, as alpha-1 antitrypsin deficiency is inherited.
Protein
- Alpha-1 Antitrypsin (AAT)
No special preparation required.
For blood tests, we recommend drinking plenty of water beforehand to ensure smooth sample collection. If you are taking any regular medication, continue to do so unless advised otherwise by your doctor.
Important Clinical Information:
This test is a screening tool to monitor and support your overall health. It does not replace your GP or consultant.
Always discuss your test results, especially any abnormal results, with your GP, who can interpret them in the context of your medical history and overall health.