Sickle Cell & Genotype Profiles - Couple
Sickle cell and thalassaemia are inherited blood disorders that can affect couples planning a family. This couple screening profile evaluates both partners' haemoglobin genotype and blood group, providing essential information about carrier status and the potential risk of passing these conditions to future children. Understanding your combined results allows you to make informed reproductive decisions with your healthcare provider.
Comparing the Standard and Plus Thalassaemia tiers helps you choose the depth of screening that matches your needs. The Standard tier offers core genotyping for sickle cell and beta thalassaemia, while the Plus tier adds alpha and gamma thalassaemia testing plus red blood cell indices and ferritin, giving a more complete picture of your blood health. Both options deliver fast, reliable results to support your family planning journey.
Blood Group & Sickle Genotype - Couple (AA, AS, SS)
- Turnaround: Same Day
- Sample: Blood
- Fasting: No fasting required
- Biomarkers: 14 analysed
Blood Group & Sickle Cell Genotype Plus Thalassaemia Screen - Couple
- Turnaround: Next Day
- Sample: Blood
- Fasting: No fasting required
- Biomarkers: 21 analysed
Biomarkers Analysed Comparison
Total 21 unique markers analysed. 14 Common 7 Differing| Biomarker Parameter |
Blood Group & Sickle Genotype - Couple (AA, AS, SS)
£250.00
Standard
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Blood Group & Sickle Cell Genotype Plus Thalassaemia Screen - Couple
£300.00
Plus Thalassaemia
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| General Biomarkers 21 markers | ||
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Blood Group - ABO
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Blood Group - RhD
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Genotype - AA,AS,AC, etc
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Genotype - HbA0
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Genotype - HbA1b
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Genotype - HbA1c
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Genotype - HbA2
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Genotype - HbC
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Genotype - HbD
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Genotype - HbF
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Genotype - HbS
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Genotype - Other variants (if present)
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Genotype - Sickle status
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β - Thalassaemia status (beta)
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Ferritin - Iron Storage
Tier Difference
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Red blood cells - HGB
Tier Difference
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Red blood cells - MCH
Tier Difference
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Red blood cells - MCV
Tier Difference
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Red blood cells - RBC
Tier Difference
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α - Thalassaemia status (alpha)
Tier Difference
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γ - Thalassaemia status (gamma if present)
Tier Difference
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Which Test Do I Need?
Which Sickle Cell & Genotype Profile is right for you?
Standard (£250.00): This tier is ideal for couples who want a foundational assessment of sickle cell and beta thalassaemia carrier status. It includes blood group typing (ABO and RhD) and comprehensive haemoglobin genotyping (HbA0, HbA2, HbF, HbA1b, HbA1c, HbC, HbS, HbD, other variants, sickle status, and beta thalassaemia status). Results are available same day. Choose this if you have no family history of alpha thalassaemia and are primarily concerned about sickle cell and beta thalassaemia risk.
Plus Thalassaemia (£300.00): This tier builds on the Standard by adding alpha and gamma thalassaemia status, along with red blood cell indices (RBC, HGB, MCV, MCH) and ferritin (iron storage). It provides a more comprehensive evaluation, including detection of alpha thalassaemia and assessment of iron status, which can be crucial for couples with unexplained anaemia or a family history of thalassaemia. Turnaround time is next day. Choose this if you want maximum diagnostic depth, especially if you have a family history of alpha thalassaemia, abnormal blood counts, or iron deficiency concerns.
Clinical Recommendation
For most couples planning a family, the Standard tier offers essential screening for sickle cell and beta thalassaemia. However, if you have a family history of alpha thalassaemia, unexplained anaemia, or want a complete blood health profile, the Plus Thalassaemia tier is recommended. Both tests require no fasting and use a simple blood sample. Discuss your results with a healthcare provider for personalised advice.
Need personalised clinical guidance?
Our clinical laboratory team in London is available to discuss your testing requirements, pre-test preparation, and help you select the most suitable health profile.