Y Chromosome Microdeletions (AZF)

Service Description

Multiplex PCR Y chromosome microdeletions are genetic abnormalities that affect the Y chromosome, which is the sex-determining chromosome in males. The Y chromosome is passed down from fathers to their sons, and it contains genes that are important for male development and fertility. Y chromosome microdeletions are characterized by small missing pieces of DNA in the Y chromosome, which can affect the function of the genes located in that region. Depending on the size and location of the deletion, Y chromosome microdeletions can result in a range of conditions, including male infertility and impaired sperm production. Y chromosome microdeletions are a relatively common cause of male infertility, accounting for up to 10-15% of cases. The deletions can be detected through genetic testing, typically through a blood or semen sample. Testing for Y chromosome microdeletions may be recommended for men who have been diagnosed with infertility or who have a family history of male infertility. While there is currently no cure for Y chromosome microdeletions, assisted reproductive technologies, such as intracytoplasmic sperm injection (ICSI), can be used to overcome fertility problems associated with these deletions. In some cases, genetic counselling may also be recommended to help individuals and couples understand the inheritance patterns of Y chromosome microdeletions and to make informed decisions about family planning. Sample: BLOOD Results:2 weeks Phlebotomy fee: £15 (included in price) Code: G13