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Thrombophilia Panel 3

Uncover your risk of blood clots, one gene at a time.

  • 15 minutes
  • 300 British pounds
  • 305 Neasden Lane, London NW10 1QR, UK

Service Description

PCR-hybridization: This test uses to detect 9 genetic variations associated with increased risk of thrombosis. These are: - Factor ΙΙ (G20210A) - Factor V (G1691A, R2 H1299A) - MTHFR (C677T,Α1298C) - Factor ΧΙΙ (V34L) - PAI-1 - EPCR (A1,A3) Factor II (G20210A) and Factor V (G1691A, R2 H1299A) are genetic variations in the Factor II and Factor V genes, respectively, that can result in an increased risk of blood clots. These variations lead to an increase in the activity of these clotting factors and have been associated with an increased risk of deep vein thrombosis, pulmonary embolism, and other thrombotic events. MTHFR (C677T, Α1298C) is a genetic variation in the MTHFR gene that affects the production of the enzyme methylenetetrahydrofolate reductase, which is involved in the metabolism of the amino acid homocysteine. These variations can lead to elevated levels of homocysteine in the blood, which has been associated with an increased risk of cardiovascular disease and thrombotic events. Factor XII (V34L) is a genetic variation in the Factor XII gene that has been associated with an increased risk of deep vein thrombosis and pulmonary embolism. PAI-1 is a protein involved in the regulation of the fibrinolytic system, which breaks down blood clots. Genetic variations in the PAI-1 gene have been associated with an increased risk of thrombotic events. EPCR (A1, A3) is a receptor found on the surface of endothelial cells that plays a role in the regulation of coagulation and inflammation. Genetic variations in the EPCR gene have been associated with an increased risk of thrombotic events. Individuals with one or more of these genetic variations may have an increased risk of developing blood clots. Genetic testing may be useful in identifying individuals who may be at increased risk, particularly in the context of other risk factors such as a personal or family history of blood clots, pregnancy, surgery, or immobility. Sample: BLOOD Results:2 weeks Phlebotomy fee: £15 (included in price)


Cancellation Policy

To cancel or schedule, please contact us 24 hours in advance


Contact Details

  • 305 Neasden Lane, London NW10 1QR, UK

    02071268511

    info@ejbio.co.uk


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