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Fibrinogen B Mutation (-455G>A)

Uncover the root cause of your bleeding problems, one gene at a time

  • 15 min
  • 125 British pounds
  • 305 Neasden Lane, London NW10 1QR, UK

Service Description

The Fibrinogen B mutation (-455G>A) is a single nucleotide variation that affects the promoter region of the FGB gene, which encodes the beta chain of fibrinogen, a blood protein involved in the formation of blood clots. This test uses PCR-Hybridization to detect the -455G>A mutation which results in a change of a guanine (G) nucleotide to an adenine (A) nucleotide at position -455 relative to the transcription start site. This alteration may affect the binding of transcription factors to the FGB promoter, leading to changes in the expression of the FGB gene. The -455G>A mutation may be associated with an increased risk of developing coronary artery disease, thrombosis, and ischemic stroke. Sample: BLOOD Results:2 weeks Phlebotomy fee: £15 (included in price)

Cancellation Policy

To cancel or schedule, please contact us 24 hours in advance

Contact Details

  • 305 Neasden Lane, London NW10 1QR, UK

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