Factor II /Prothrombin Mutation (G20210)

Service Description

Factor II, also known as prothrombin, is a protein that plays a role in the clotting of blood. This test uses Real-Time PCR to detect G20210A mutation, which is a genetic variation in the Factor II gene that is associated with an increased risk of blood clots, particularly in the veins (venous thromboembolism). The G20210A mutation increases the production of prothrombin, which can lead to an increased tendency for blood clotting. Studies have shown that individuals who carry the G20210A mutation have a higher risk of developing venous thromboembolism, particularly deep vein thrombosis (DVT) and pulmonary embolism (PE). The G20210A mutation is inherited in an autosomal dominant pattern, which means that an affected person only needs to inherit one copy of the mutated gene to develop the condition. However, not all individuals with this mutation will develop blood clots. Testing for the G20210A mutation may be recommended in individuals with a personal or family history of venous thromboembolism or unexplained clotting disorders. Individuals who test positive for the mutation may be advised to take steps to reduce their risk of blood clots, such as avoiding smoking, maintaining a healthy weight, and avoiding prolonged periods of immobility. In some cases, individuals with the G20210A mutation may be advised to take anticoagulant medications to reduce their risk of blood clots. However, the decision to take these medications should be made on an individual basis and in consultation with your doctor, taking into account the individual's overall health, medical history, and other factors. Sample: BLOOD Results:2 weeks Phlebotomy fee: £15 (included in price)